The phage shock protein response
WebbThe Psp response was discovered by Peter Model and his colleagues at the Rockefeller University in New York City. They noticed that infection of Escherichia coli cells by the filamentous phage f1 and production of the phage-encoded secretin (a pore-forming protein) caused massive production of a bacterial protein they called PspA [ 8 ]. WebbThe phage shock protein (Psp) system is a conserved extracytoplasmic stress response in bacteria that is essential for virulence of the human pathogen Yersinia enterocolitica. …
The phage shock protein response
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Webb(Figure 1). Filamentous phage infection induces pspA operon expression because a phage-encoded outer membrane pore-forming ‘‘secretin’’ protein (pIV) has a tendency to mislocalize within the E. coli envelope [3]. The Psp response is also induced by environmental shocks that can negatively affect the cell envelope. This, together with ... WebbStress relief during host infection: The phage shock protein response supports bacterial virulence in various ways. Stress relief during host infection: The phage shock protein …
Webb28 juli 2006 · The phage shock protein (Psp) F regulon response in Escherichia coli is thought to be induced by impaired inner membrane integrity and an associated decrease … Webb1 aug. 2005 · The phage‐shock‐protein response Darwin, Andrew J. 2005-08-01 00:00:00 Introduction The Gram‐negative bacterial cell envelope controls the passage of molecules into and out of the cell, includes structures like the cell wall, flagella and complex secretion systems, and provides an ion‐permeability barrier for the establishment of the …
WebbThe phage shock protein (Psp) F regulon response in Escherichia coli is thought to be induced by impaired inner membrane integrity and an associated decrease in proton motive force (pmf). Mechanisms by which the Psp system detects the stress signal and responds have so far remained undetermined. Here we demonstrate that PspA and PspG directly … Webb11 juli 2013 · The “phage shock” name comes from the founding discovery that filamentous phage f1 infection massively induces the synthesis of an E. coli protein, which was …
WebbThe phage shock protein (Psp) stress response is one such conserved protection network. Most knowledge about the Psp response derives from studies in the Gram-negative …
Webb31 dec. 2004 · The phage shock protein operon (pspABCDE) of Escherichia coli is strongly up-regulated in response to overexpression of the filamentous phage secretin protein IV … great falls housing marketWebbThe phage shock protein (Psp) system was identified as a response to phage infection in Escherichia coli, but rather than being a specific response to a phage, it detects and … fliptop softwareWebb15 juni 2004 · Model for the cold shock response and adaptation after the temperature downshift from 37° to ( A) 15°C and ( B) 0 to 4°C (near-freezing) in E. coli and yeast. I, optimal growth at 37°C; II, Acclimation phase; III, steady low-temperature growth; Csps, cold shock proteins; Tps1, trehalose-6-phosphate-synthase; Tps2, trehalose-6-phosphate … great falls humane societyWebb1 sep. 2005 · The phage shock protein (Psp) stress-response system protects bacteria from envelope stress through a cascade of interactions with other proteins and … flip top sofa/console tableWebbThe Phage shock protein (Psp) response maintains bacterial membrane integrity during extracytoplasmic stress. The central component of this system is a 2 5 kDa protein, which was observed during filamentous phage infection in Escherichia coli but was absent in non-infected cells [1]. great falls hsgreat falls hs scWebbThe Phage shock protein (Psp) response is an extracytoplasmic stress response. The central component of this system is PspA, a protein that mediates the physiological response to membrane stress. PspA is also involved in regulating its own transcription and that of the psp operon, forming a positive feedback loop. PspA has been previously … great falls hydro plant