Hoip protein
NettetIts body is so light, it must grip the ground firmly with its feet to keep from being blown away. It drifts on winds. It is said that when Hoppip gather in fields and mountains, … NettetBioinformatics Protein Aliases: E3 ubiquitin-protein ligase RNF31; FLJ23501; HOIL-1-interacting protein; HOIP; MGC19975; RING finger protein 31; RING-type E3 ubiquitin transferase RNF31; Zinc in-between-RING-finger ubiquitin-associated domain protein Gene Aliases: HOIP; RNF31; ZIBRA UniProt ID: (Human) Q96EP0 Entrez Gene ID: …
Hoip protein
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NettetLineage Also known as HOIP; Paul; ZIBRA Summary The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Nettet8. mai 2014 · Linear ubiquitin chains are implicated in the regulation of the NF-κB pathway, immunity, and inflammation. They are synthesized by the LUBAC complex containing the catalytic subunit HOIL-1-interacting protein (HOIP) and are disassembled by the linear ubiquitin-specific deubiquitinase OTULIN.
NettetInvitrogen Anti-HOIP Polyclonal, Catalog # PA5-114380. Tested in Western Blot (WB) and ELISA (ELISA) applications. This antibody reacts with Human, Mouse, Rat samples. … Nettet11. mar. 2024 · It is well established that this trimeric complex, comprising HOIL-1, HOIP (HOIL-1-interacting protein) and Sharpin (Shank-associated RH domain interactor), is required in signal transduction pathways that generate inflammatory mediators or lead to cell death (Gerlach et al, 2011; Ikeda et al, 2011; Tokunaga et al, 2011; Ikeda, 2015; …
Nettet6. aug. 2024 · HOIP elevation appears to be specifically required to signal protection from genotoxic stress, but how precisely does the E3 ligase activity promote this program and what are its relevant substrates in this process? Clearly, HOIP elevation alone is insufficient to induce lymphoma. Nettet2. mar. 2024 · d Western blot analysis of HOIP proteins in HEK293T cells infected with VSV (MOI = 0.1) as indicated. e Immunoprecipitation analysis of the interaction …
Nettet3. okt. 2024 · The protein expression levels of HOIP in xenograft tumors were validated by immunoblotting analysis (Fig. S 1I ). Taken together, the results demonstrate that HOIP promotes PCa progression...
Nettet5. feb. 2024 · The HOIP component of the linear ubiquitin assembly complex catalyzes the formation of M1-polyubiquitin chains in response to interleukin-1. The data showed how … choosing an electric radiator fanNettet2. mar. 2024 · During the identification of the signaling regulators of the transcription factor STAT1 activation, we noticed that the ubiquitin E3 ligase RNF31, also known as HOIP, was repeatedly observed... great american coin searchNettetHOIP-UB is a binding domain on E3 ubiquitin-protein ligase RNF31 like proteins. E3 ubiquitin-protein ligase RNF31 is often referred to as HOIL-1L binding partner. The interaction of HOIL-1L and HOIP is thus via the UBL-UBA interaction. this interaction is important in E3 complex formation and the subsequent activation of NF-kappaB. choosing an electric space heaterNettet3. apr. 2024 · The LUBAC ubiquitin ligase complex, composed of the HOIP, HOIL-1L, ... Interestingly, genetic mutations of LUBAC subunits and linear ubiquitin-binding proteins induce various disorders 20. great american coinschoosing an easy to clean kitchen sinkNettetOutside of cold regions, Hoppip can be found practically everywhere. This is because the wind carries this species all over the world. choosing an electric provider for my businessNettet3. okt. 2024 · The E3 activity of HOIP can be effectively activated by HOIL-1L or SHARPIN, deficiency of which leads to severe immune system disorders. However, the underlying mechanism governing the HOIP-SHARPIN interaction and the SHARPIN-mediated activation of HOIP remains elusive. choosing an electric toothbrush